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Check Out What's Making Waves in the Field of Constipation Research
New constipation therapies are making waves in the field of constipation research today. The three new promising constipation therapies include lubiprostone (type-2 chloride channel activator), Anorectal biofeedback and probiotics.
Recent studies in constipation research have proven the efficacy of the three constipation therapies mentioned. These constipation therapies have greatly alleviated the chronically constipated participants of the study.
Statistics say that chronic constipation yields an estimated 30,000 to 90,000 hospitalizations annually and an estimated over 2 million doctor visits annually.
This is why more and more people are paving the way for a more fruitful and more aggressive constipation research.
An Evaluation of New Constipation Therapies
Evidence of the efficacy of the three novel constipation therapies was evaluated in a symposium in concurrence with the Digestive Disease Week. The symposium concluded that all three constipation therapies are effective and have been proven to be safe.
The FDA approved Lubiprostone, the type-2 chloride channel activator proved to be an effective treatment for adult chronic idiopathic constipation. According to the constipation research, in comparison with placebo, lubiprostone greatly heightened the bowel movement of the participants in just four weeks.
Compared with the 31% efficacy rate of the placebo treated participants, lubiprostone proved to be more effective with its 61% efficacy rate of increasing bowel movements. It has also shown to be well tolerated with only diarrhea, headache and nausea as common side effects.
Anorectal biofeedback is the retraining of bowels and muscles. This is done by inserting an electronic probe or small balloon in your anus and then evaluating how your bowels and muscles work.
In the study, 65 % of the patients who used Anorectal biofeedback were satisfied and had more spontaneous bowel movements after three months of therapy as opposed to the 40% satisfaction rate of the patients on placebo.
Probiotics are live microorganisms like Bifidobacterium animalis and Lactobacillus species and yeasts. They improve the balance of the intestinal environment when ingested. Probiotics have been studied for years and has been proven to beneficially affect intestinal and stomach related problems.
In study where 72 volunteers, all adults were asked to drink fermented milk with Bifidobacterium animalis daily, it has been proven that sigmoid transit time was reduced by 39% and the colonic transit time reduced to 21%. It was concluded that probiotics help constipated patients through improved bowel movements.